Chemical Name:(16(Alpha),17(Beta)) - Estra-1,3,5(10) –triene–3,16,17–triol
Molecular Formula: C18H24O3
Molecular Weight: 288.39
CAS: 50-27-1

Estriol Description and Indication

Estriol is a major urinary estrogen, and the weakest of the three major estrogens in body. It is produced during pregnancy and is the major estrogen produced in the normal human fetus. During pregnancy the production of Estriol depends on an intact maternal-placental-fetal unit. Estriol levels in non-pregnant women do not change much after menopause. It is only produced in significant amounts during pregnancy as it is made by the placenta.

In pregnant women with multiple sclerosis, Estriol reduces the disease´s symptoms noticeably. It helps relieve menopausal symptoms and may also help improve cardiovascular risk factors and in reducing the brain lesions caused by multiple sclerosis.

Estriol is commonly indicated in the following cases:

Estriol Mechanism of Action

Estriol is a naturally occurring estrogen. It induces normalization of the vaginal epithelium. Additionally, it is claimed to have only a mild proliferative effect on the endometrium and a short retention time in the nuclei of endometrial cells.

Estriol Contraindications

Estriol is contraindicated in patients with the following conditions:

Estriol Adverse Drug Effects

Estriol Drug Interactions

Estriol Formulations

Estriol Brands

These are the following brands available for Estriol: